KUMJ | VOL. 20 | NO. 2 | ISSUE 78 | APRIL - JUNE 2022

Rhino-Orbital Mucormycosis in a COVID-19 Patient: A Dreadful Challenge
Dhakal A, Pokharel M, Madhup S, Khadka L, Sapkota B

Abstract:
Coronavirus disease 2019 (COVID-19) is a pandemic disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-COV-2). COVID-19 infections may be associated with a wide range of bacterial and fungal co-infections. Recent studies are reporting invasive fungal infection associated with severe COVID-19. Herein, we report a case of COVID-19 rhino-orbital mucormycosis infection caused by Rhizopus sps in a 32 year old diabetic patient who was successfully managed with early aggressive debridement of infected tissue endoscopically with extended ethmoidectomy by modified Denker �s approach along with orbital decompression and antifungal therapy with Liposomal Amphotericin B and Posaconazole. Serial diagnostic nasal endoscopy showed no evidence of progression of the infection. The patient was discharged on 21st day of hospitalizati on still on oral Posaconazole for a total of 3 months.
Keyword : Amphotericin B, Covid-19, Mucormycosis, Surgical debridement