KUMJ | VOL. 24 | NO. 3 | ISSUE 96 | JULY-SEPTEMBER, 2026
Clinical and Procedural Determinants of Cumulative Air Kerma During Coronary Angiography and Percutaneous Coronary Intervention: A Prospective Observational Study
KC B, Gautam S, Dhungel S, Shakya A, Khan M, Ghimire JP, Thapa B
Abstract: Background
Radiation exposure remains an important safety concern during fluoroscopy-guided
coronary procedures. Cumulative air kerma is a useful indicator of patient radiation
exposure.
Objective
To identify clinical and procedural determinants of radiation exposure, measured
as cumulative air kerma, during coronary angiography and percutaneous coronary
intervention.
Method
We prospectively studied 723 consecutive patients undergoing coronary angiography
and/or percutaneous coronary intervention between June 15, 2025, and June 15,
2026. Demographic, clinical, angiographic, procedural, and radiation exposure
data were collected. Univariable analyses identified factors associated with logtransformed
cumulative air kerma, followed by multivariable linear regression to
determine independent predictors.
Result
Of 723 procedures, 353 (48.8%) were diagnostic coronary angiography and 370
(51.2%) were percutaneous coronary intervention. Procedure type, vascular access,
fluoroscopy time, number of vessels and lesions treated, total stent length, and
number of implanted stents was significantly associated with log-transformed
cumulative air kerma in univariable analysis (all p < 0.05). The multivariable model
was statistically significant (p < 0.001) and explained 69.6% of the variability in
radiation exposure (adjusted R² = 0.693). Fluoroscopy time (β = 0.495, p < 0.001),
percutaneous coronary intervention versus coronary angiography (β = 0.390, p <
0.001), female versus male sex (β = −0.107, p < 0.001), and femoral versus radial
access (β = −0.055, p = 0.009) were independent predictors. Age, clinical indication,
lesion type, and total stent length were not independently associated with cumulative
air kerma.
Conclusion
Fluoroscopy time and procedure type were the strongest independent predictors of
cumulative air kerma, highlighting procedural complexity as a major determinant of
radiation exposure.
Keyword : Coronary angiography, Fluoroscopy, Percutaneous coronary intervention, Radiation exposure